The Resource for your Nonhuman Primate Research

We support innovation, reproducibility, and translation of preclinical research with high-quality biological development. We offer primate antibodies and recombinant proteins for pre-clinical NHP studies, NHP-specific reagents for in vitro assays, and have an industry wide antibody reactivity database for NHP species.

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NHP Reactivity

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2026 April 15

a4 Integrin blockade impairs CD8+ T cell neuroimmune surveillance following SIV infection.

Pal, Pabitra B Elizaldi, Sonny R Diniz, Giovanne B Rai, Ravi Prakash Shaan Lakshmanappa, Yashavanth Verma, Anil Rossmiller, Daniel Kaufman, Jesse Srivastava, Rahul Ott, Sean Erices, Carissa T Schwartz, Kayla Beckman, Danielle Ma, Zhong-Min Petkov, Alex Newhouse, Daniel Rajasundaram, Dhivyaa Morrison, John H Raeman, Reben Iyer, Smita S

J Clin Invest

Anti-alpha4/beta7 [A4B7R1] Control antibody rhesus IgG1 (anti-DSP) [DSPR1]

2026 February 13

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development.

Habib, Rumi Roark, Ryan S Li, Hui Connell, Andrew Jesse Hogarty, Michael P Wagh, Kshitij Wang, Shuyi Marchitto, Lorie Skelly, Ashwin N Carey, John W Sowers, Kirsten J Ayyanathan, Kasirajan Plante, Samantha J Bibollet-Ruche, Frederic Park, Younghoon Agostino, Colby J Singh, Ajay Martella, Christian L Lewis, Emily Rando, Juliette M Chohan, Neha Lora, Jinery Ding, Wenge Campion, Mary S Zhao, Chengyan Liu, Weimin Li, Yingying Li, Xuduo Liang, Bo Chowdhury, Rohan Roy Amereh, Khaled Van Itallie, Elizabeth Sheng, Zizhang Ghosh, Amrit R Bar, Katharine J Williams, Wilton B Wiehe, Kevin Saunders, Kevin O Edwards, Robert J Cain, Derek W Lewis, Mark G Batista, Facundo D Burton, Dennis R Andrabi, Raiees Kulp, Daniel W Haynes, Barton F Korber, Bette Shapiro, Lawrence Kwong, Peter D Hahn, Beatrice H Shaw, George M

Sci Immunol

Anti-CD8 beta [CD8b255R1] Anti-CD8 alpha [MT807R1]

2026 January 31

Functional antibody signatures following therapeutic immunization in Simian and Human immunodeficiency virus infection.

Ilan, Shlomi Bartsch, Yannic Jung, Wonyeong Kliuchnikov, Evgenii Roy, Vicky Bonifer, Riley Walker-Sperling, Victoria E K Borducchi, Erica N Nkolola, Joseph P Lauffenburger, Douglas A Stieh, Daniel J Barouch, Dan H Julg, Boris

NPJ Vaccines

Anti-rhesus IgG4 [tessera] Anti-rhesus IgG2 [dio] Anti-rhesus IgG3 [tria] Anti-rhesus IgA [9B9] Anti-rhesus IgG1 [ena]

News & Updates:

2024 Aug 23

mAbsolve Parnership for Fc-silenced STR Antibodies

Today, we celebrate a milestone—partnering with mAbsolve to incorporate ‘STR’ mutations into our antibodies. This ensures targeted action without unintended immune responses, boosting rigor, effectiveness, and safety. By decreasing Fc-mediated interference (hello Fc-block!) and enhancing the signal-to-noise ratio, STR-enhanced antibodies will produce more robust and reproducible scientific findings. Expect many STR-enhanced antibodies soon!

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2024 Apr 09

For your Acknowledgements section

Reagents used in these studies were provided by the NIH Nonhuman Primate Reagent Resource (P40 OD028116, U24 AI126683).

2024 Apr 11

NHPRR Linkedin

Follow our newest publications, products, and messages on LinkedIn!

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2024 Apr 09

RRID Citation on Materials and Methods

For your Materials & Methods section: The rhesus recombinant Anti-CD8 beta [CD8b255R1] monoclonal antibody was engineered and produced by the Nonhuman Primate Reagent Resource (NIH Nonhuman Primate Reagent Resource Cat# PR-2557, RRID:AB_2716321)

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Sharing Your Data: Our community-based reactivity database is built by users like you. Share your results!

Requesting a Reagent: We develop NHP-specific antibodies based on investigator-initiated requests, including: recombinant proteins for cell depletion, receptor activation, cytokine neutralization, co-stimulatory blockade, immunosuppression.

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