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Publications Using Our Reagents

See publications using our reagents to inform your research. If you have recently published a study using a NHPRR reagent, you can now add submit it directly to the publication database.

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2021 June 07

Antibody-based CCR5 blockade protects Macaques from mucosal SHIV transmission

Xiao L Chang, Gabriela M Webb, Helen L Wu, Justin M Greene, Shaheed Abdulhaqq, Katherine B Bateman, Jason S Reed, Cleiton Pessoa, Whitney C Weber, Nicholas Maier, Glen M Chew, Roxanne M Gilbride, Lina Gao, Rebecca Agnor, Travis Giobbi, Jeffrey Torgerson, Don Siess, Nicole Burnett, Miranda Fischer, Oriene Shiel, Cassandra Moats, Bruce Patterson, Kush Dhody, Scott Kelly, Nader Pourhassan, Diogo M Magnani, Jeremy Smedley, Benjamin N Bimber, Nancy L Haigwood, Scott G Hansen, Timothy R Brown, Lishomwa C Ndhlovu, Jonah B Sacha

Nat Commun

Anti-rhesus IgG1/3 [1B3]-HRP

2021 June 02

Measuring the Impact of Targeting FcRn-Mediated IgG Recycling on Donor-Specific Alloantibodies in a Sensitized NHP Model

Miriam Manook, Walter J. Flores, Robin Schmitz, Zachary Fitch, Janghoon Yoon, Yeeun Bae, Brian Shaw, Allan Kirk, Melissa Harnois, Sallie Permar, Alton B. Farris, Diogo M. Magnani, Jean Kwun and Stuart Knechtle

Front. Immunol.

Anti-FcRn [RozR1LALA]

2021 May 21

A comparative study of human-and rhesus-specific antithymocyte globulins in Rhesus macaques

Brian I Shaw, Robin Schmitz, Walter J Flores, Diogo M Magnani, Jie Li, Mingqing Song, Allan D Kirk

Clin Transplant

Anti-rhesus thymocyte [rhATG] - (all lots)

2021 April 09

Zika virus infection during pregnancy protects against secondary infection in the absence of CD8 + cells

Blake Schouest, Brandon J Beddingfield, Margaret H Gilbert, Rudolf P Bohm, Faith Schiro, Pyone P Aye, Antonito T Panganiban, Diogo M Magnani, Nicholas J Maness

Virology

Anti-CD8 alpha [MT807R1]

2021 March 01

CD4+/CD8+ T cell ratio correlates with the graft fate in pig-to-nonhuman primate islet xenotransplantation

Hyunwoo Chung, Hyun-Je Kim, Jung-Sik Kim, Il-Hee Yoon, Byoung-Hoon Min, Jun-Seop Shin, Jong-Min Kim, Won-Woo Lee and Chung-Gyu Park

Xenotransplantation

Anti-CD40 [2C10R4] Anti-CD154 [5C8H1]

2021 February 17

Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies.

Pedreño-Lopez N, Dang CM, Rosen BC, Ricciardi MJ, Bailey VK, Gutman MJ, Gonzalez-Nieto L, Pauthner MG, Le K, Song G, Andrabi R, Weisgrau KL, Pomplun N, Martinez-Navio JM, Fuchs SP, Wrammert J, Rakasz EG, Lifson JD, Martins MA, Burton DR, Watkins DI, Magnani DM

Molecular therapy. Methods & clinical development

Anti-CD8 beta [CD8b255R1]

2021 February 01

Mucosal integrin α4β7 blockade fails to reduce the seeding and size of viral reservoirs in SIV-infected rhesus macaques

Widade Ziani, Jiasheng Shao, Angela Fang, Patrick J Connolly, Xiaolei Wang, Ronald S Veazey, Huanbin Xu

FASEB J

Anti-alpha4/beta7 [A4B7R1]

2020 September 05

Preoperative Carfilzomib and Lulizumab based desensitization prolongs graft survival in a sensitized non-human primate model

Paul M Schroder , Robin Schmitz, Zachary W Fitch, Brian Ezekian, Janghoon Yoon, Ashley Y Choi, Miriam Manook, Andrew Barbas, Frank Leopardi, Mingqing Song, Alton B Farris, Bradley Collins, Jean Kwun, Stuart J Knechtle

Kidney Int

Anti-rhesus thymocyte [rhATG] - (all lots)

2020 August 05

PD-1 blockade exacerbates Mycobacterium tuberculosis infection in rhesus macaques

Keith D Kauffman, Shunsuke Sakai, Nickiana E Lora, Sivaranjani Namasivayam, Paul J Baker, Olena Kamenyeva, Taylor W Foreman, Christine E Nelson, Deivide Oliveira-de-Souza, Caian L. Vinhaes, Ziv Yaniv, Cecilia S Lindestam Arleham, Alessandro Sette, Gordon J Freeman, Rashida Moore, the NIAID/DIR Tuberculosis Imaging Program, Alan Sher, Katrin D Mayer-Barber, Bruno B Andrade, Juraj Kabat, Laura E Via, Daniel L Barber

Bio

Anti-PD1 [NIVOR4LALA]

2020 February 13

Induction of Transient Virus Replication Facilitates Antigen-Independent Isolation of SIV-Specific Monoclonal Antibodies

Nuria Pedreño-Lopez, Christine M Dang, Brandon C Rosen, Michael J Ricciardi, Varian K Bailey, Martin J Gutman, Lucas Gonzalez-Nieto, Matthias G Pauthner, Khoa Le, Ge Song, Raiees Andrabi, Kim L Weisgrau, Nicholas Pomplun, José M Martinez-Navio, Sebastian P Fuchs, Jens Wrammert, Eva G Rakasz, Jeffrey D Lifson, Mauricio A Martins, Dennis R Burton, David I Watkins, Diogo M Magnani

Mol Ther Methods Clin Dev

Anti-CD8 beta [CD8b255R1]

2020 February 01

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 + cells

Julia Bergild McBrien, Maud Mavigner, Lavinia Franchitti, S Abigail Smith, Erick White, Gregory K Tharp, Hasse Walum, Kathleen Busman-Sahay, Christian R Aguilera-Sandoval, William O Thayer, Rae Ann Spagnuolo, Martina Kovarova, Angela Wahl, Barbara Cervasi, David M Margolis, Thomas H Vanderford, Diane G Carnathan, Mirko Paiardini, Jeffrey D Lifson, John H Lee, Jeffrey T Safrit, Steven E Bosinger, Jacob D Estes, Cynthia A Derdeyn, J Victor Garcia, Deanna A Kulpa, Ann Chahroudi, Guido Silvestri

Nature

Anti-CD8 alpha [MT807R1]

2020 January 01

Safety and pharmacodynamics of anti-CD2 monoclonal antibody treatment in cynomolgus macaques – an experimental study

Berglund et al.

Transplant International

Anti-CD2 [LoCD2bR1]

2019 December 01

Pretransplant Desensitization with Costimulation Blockade and Proteasome Inhibitor Reduces DSA and Delays Antibody-Mediated Rejection in Highly Sensitized Nonhuman Primate Kidney Transplant Recipients

Brian Ezekian, Paul M Schroder, Michael S Mulvihill, Andrew Barbas, Bradley Collins, Kyle Freischlag, Janghoon Yoon, John S Yi, Felicitas Smith, Danae Olaso, Frances M Saccoccio, Sallie Permar, Alton B Farris, Jean Kwun, Stuart J Knechtle

J Am Soc Nephrol

Anti-CD4 [CD4R1] Anti-CD8 alpha [MT807R1]

2019 October 22

Acute Infection and Subsequent Subclinical Reactivation of Herpes Simplex Virus 2 after Vaginal Inoculation of Rhesus Macaques.

Lo M, Zhu J, Hansen SG, Carroll T, Farr Zuend C, Nöel-Romas L, Ma ZM, Fritts L, Huang ML, Sun S, Huang Y, Koelle DM, Picker LJ, Burgener A, Corey L, Miller CJ

Journal of virology

Anti-CD8 alpha [MT807R1] Anti-IL-15 [IL-15R1LALA]

2019 September 23

TLR7 agonists induce transient viremia and reduce the viral reservoir in SIV-infected rhesus macaques on antiretroviral therapy.

Lim SY, Osuna CE, Hraber PT, Hesselgesser J, Gerold JM, Barnes TL, Sanisetty S, Seaman MS, Lewis MG, Geleziunas R, Miller MD, Cihlar T, Lee WA, Hill AL, Whitney JB

Science translational medicine

Anti-CD8 alpha [MT807R1] Anti-CD38 [OKT10]-PE

2019 September 06

Lack of therapeutic efficacy of an antibody to α4 β7 in SIVmac251-infected rhesus macaques

Peter Abbink, Noe B Mercado, Joseph P Nkolola, Rebecca L Peterson, Hubert Tuyishime, Katherine McMahan, Edward T Moseley, Erica N Borducchi, Abishek Chandrashekar, Esther A Bondzie, Arshi Agarwal, Aaron J Belli, Keith A Reimann, Brandon F Keele, Romas Geleziunas, Mark G Lewis, Dan H Barouch

Science

Anti-alpha4/beta7 [A4B7R1] Control antibody rhesus IgG1 (anti-DSP) [DSPR1]

2019 July 01

Daratumumab in Sensitized Kidney Transplantation: Potentials and Limitations of Experimental and Clinical Use

Jean Kwun, Marie Matignon, Miriam Manook, Soulef Guendouz, Vincent Audard, David Kheav, Elsa Poullot, Chantal Gautreau, Brian Ezekian, Diane Bodez, Thibault Damy, Laureline Faivre, Dehbia Menouch, Janghoon Yoon, Jaeberm Park, Karim Belhadj, Dongfeng Chen, Alyssa M Bilewski, John S Yi, Bradley Collins, Mark Stegall, Alton B Farris, Stuart Knechtle, Philippe Grimbert

J Am Soc Nephrol

Anti-CD4 [CD4R1] Anti-CD8 alpha [MT807R1]

2019 May 13

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.

Okoye AA, Hansen SG, Vaidya M, Fukazawa Y, Park H, Duell DM, Lum R, Hughes CM, Ventura AB, Ainslie E, Ford JC, Morrow D, Gilbride RM, Legasse AW, Hesselgesser J, Geleziunas R, Li Y, Oswald K, Shoemaker R, Fast R, Bosche WJ, Borate BR, Edlefsen PT, Axthelm MK, Picker LJ, Lifson JD

Nature medicine

Anti-CD8 alpha [MT807R1]

2019 April 05

Mucosal and systemic SIV-specific cytotoxic CD4+ T cell hierarchy in protection following intranasal/intramuscular recombinant pox-viral vaccination of pigtail macaques.

Khanna, Mayank; Jackson, Ronald J; Alcantara, Sheilajen; Amarasena, Thakshila H; Li, Zheyi; Kelleher, Anthony D; Kent, Stephen J; Ranasinghe, Charani

Scientific Reports

Legacy Product

2019 March 19

A Pathogenic Role for Splenic B1 Cells in SIV Disease Progression in Rhesus Macaques.

Enyindah-Asonye, Gospel; Nwankwo, Anthony; Hogge, Christopher; Rahman, Mohammad Arif; Helmold Hait, Sabrina; Hunegnaw, Ruth; Ko, Eun-Ju; Hoang, Tanya; Venzon, David J; Robert-Guroff, Marjorie

Frontiers in Immunology

Legacy Product

2019 March 01

Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients

Christopher K Burghuber, Miriam Manook, Brian Ezekian, Adriana C Gibby, Frank V Leopardi, Minqing Song, Jennifer Jenks, Frances Saccoccio, Sallie Permar, Alton B Farris, Neal N Iwakoshi, Jean Kwun, Stuart J Knechtle

Am J Transplant

Anti-CD4 [CD4R1] Anti-CD8 alpha [MT807R1]

2019 February 20

Introduction of the YTE mutation into the non-immunogenic HIV bnAb PGT121 induces anti-drug antibodies in macaques.

Rosenberg, Yvonne J; Lewis, George K; Montefiori, David C; LaBranche, Celia C; Lewis, Mark G; Urban, Lori A; Lees, Jonathan P; Mao, Lingjun; Jiang, Xiaoming

PloS One

Legacy Product

2019 February 12

Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys.

Borducchi EN, Liu J, Nkolola JP, Cadena AM, Yu WH, Fischinger S, Broge T, Abbink P, Mercado NB, Chandrashekar A, Jetton D, Peter L, McMahan K, Moseley ET, Bekerman E, Hesselgesser J, Li W, Lewis MG, Alter G, Geleziunas R, Barouch DH

Nature

Anti-CD8 alpha [MT807R1]

2019 January 17

Reactivation of Simian Varicella Virus in Rhesus Macaques after CD4 T Cell Depletion

Vicki Traina-Dorge, Brent E Palmer, Colin Coleman, Meredith Hunter, Amy Frieman, Anah Gilmore, Karen Altrock, Lara Doyle-Meyers, Maria A Nagel, Ravi Mahalingam

J Virol

Anti-CD4 [CD4R1]

2019 January 01

Hybrid nanocarriers incorporating mechanistically distinct drugs for lymphatic CD4+ T cell activation and HIV-1 latency reversal.

Cao, Shijie; Slack, Sarah D; Levy, Claire N; Hughes, Sean M; Jiang, Yonghou; Yogodzinski, Christopher; Roychoudhury, Pavitra; Jerome, Keith R; Schiffer, Joshua T; Hladik, Florian; Woodrow, Kim A

Science Advances

Anti-CD4 [CD4R1] Control antibody rhesus IgG1 (anti-DSP) [DSPR1]

2018 December 17

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche.

Sosa, Enrique; Chen, Di; Rojas, Ernesto J; Hennebold, Jon D; Peters, Karen A; Wu, Zhuang; Lam, Truong N; Mitchell, Jennifer M; Sukhwani, Meena; Tailor, Ramesh C; Meistrich, Marvin L; Orwig, Kyle E; Shetty, Gunapala; Clark, Amander T

Nature Communications

Legacy Product

2018 December 10

Subclinical Infection of Macaques and Baboons with A Baboon Simarterivirus.

Buechler, Connor; Semler, Matthew; Baker, David A; Newman, Christina; Cornish, Joseph P; Chavez, Deborah; Guerra, Bernadette; Lanford, Robert; Brasky, Kathy; Kuhn, Jens H; Johnson, Reed F; O'connor, David H; Bailey, Adam L

Viruses

Legacy Product

2018 November 27

Antibody responses to Zika virus proteins in pregnant and non-pregnant macaques.

Heffron, Anna S; Mohr, Emma L; Baker, David; Haj, Amelia K; Buechler, Connor R; Bailey, Adam; Dudley, Dawn M; Newman, Christina M; Mohns, Mariel S; Koenig, Michelle; Breitbach, Meghan E; Rasheed, Mustafa; Stewart, Laurel M; Eickhoff, Jens; Pinapati, Richard S; Beckman, Erica; Li, Hanying; Patel, Jigar; Tan, John C; O'connor, David H

PloS Neglected Tropical Diseases

Anti-primate IgG [8F1]-biotin

2018 November 02

Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing.

Mohseni Ahooyi, Taha; Shekarabi, Masoud; Torkzaban, Bahareh; Langford, T Dianne; Burdo, Tricia H; Gordon, Jennifer; Datta, Prasun K; Amini, Shohreh; Khalili, Kamel

Scientific Reports

Anti-CD8 alpha [MT807R1]

2018 October 25

Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation.

Colonna, Lucrezia; Peterson, Christopher W; Schell, John B; Carlson, Judith M; Tkachev, Victor; Brown, Melanie; Yu, Alison; Reddy, Sowmya; Obenza, Willi M; Nelson, Veronica; Polacino, Patricia S; Mack, Heather; Hu, Shiu-Lok; Zeleski, Katie; Hoffman, Michelle; Olvera, Joe; Furlan, Scott N; Zheng, Hengqi; Taraseviciute, Agne; Hunt, Daniel J; Betz, Kayla; Lane, Jennifer F; Vogel, Keith; Hotchkiss, Charlotte E; Moats, Cassie; Baldessari, Audrey; Murnane, Robert D; English, Christopher; Astley, Cliff A; Wangari, Solomon; Agricola, Brian; Ahrens, Joel; Iwayama, Naoto; May, Andrew; Stensland, Laurence; Huang, Meei-Li W; Jerome, Keith R; Kiem, Hans-Peter; Kean, Leslie S

Nature Communications

Anti-Mamu A*01 [P12]-PE

2018 September 27

Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells.

Mudd, Joseph C; Busman-Sahay, Kathleen; DiNapoli, Sarah R; Lai, Stephen; Sheik, Virginia; Lisco, Andrea; Deleage, Claire; Richardson, Brian; Palesch, David J; Paiardini, Mirko; Cameron, Mark; Sereti, Irini; Reeves, R Keith; Estes, Jacob D; Brenchley, Jason M

Nature Communications

Anti-CD4 [CD4R1] Control antibody rhesus IgG1 (anti-DSP) [DSPR1]

2018 September 05

IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells.

Blasi, Maria; Negri, Donatella; LaBranche, Celia; Alam, S Munir; Baker, Erich J; Brunner, Elizabeth C; Gladden, Morgan A; Michelini, Zuleika; Vandergrift, Nathan A; Wiehe, Kevin J; Parks, Robert; Shen, Xiaoying; Bonsignori, Mattia; Tomaras, Georgia D; Ferrari, Guido; Montefiori, David C; Santra, Sampa; Haynes, Barton F; Moody, Michael A; Cara, Andrea; Klotman, Mary E

Communications Biology

Legacy Product

2018 September 01

MAdCAM costimulation through Integrin-alpha4/beta7 promotes HIV replication.

Nawaz, Fatima; Goes, Livia R; Ray, Jocelyn C; Olowojesiku, Ronke; Sajani, Alia; Ansari, Aftab A; Perrone, Ian; Hiatt, Joseph; Van Ryk, Donald; Wei, Danlan; Waliszewski, Mia; Soares, Marcelo A; Jelicic, Katija; Connors, Mark; Migueles, Stephen A; Martinelli, Elena; Villinger, Francois; Cicala, Claudia; Fauci, Anthony S; Arthos, James

Mucosal Immunology

2018 August 30

Inhibition of p38 MAPK in combination with ART reduces SIV-induced immune activation and provides additional protection from immune system deterioration.

Chaudhary, Omkar; Narayan, Vivek; Lelis, Felipe; Linz, Brandon; Watkins, Meagan; Veazey, Ronald; Aldovini, Anna

PloS Pathogens

Anti-CD38 [OKT10]-APC

2018 August 28

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to alpha4/beta7.

Lertjuthaporn et al.

PloS Pathogens

Anti-alpha4/beta7 [A4B7R1] Control antibody rhesus IgG1 (anti-DSP) [DSPR1]

2018 August 22

Two Vaccines for Staphylococcus aureus Induce a B-Cell-Mediated Immune Response.

Dupont, Christopher D; Scully, Ingrid L; Zimnisky, Ross M; Monian, Brinda; Rossitto, Christina P; O'connell, Ellen B; Jansen, Kathrin U; Anderson, Annaliesa S; Love, J Christopher

MSphere

Anti-CD38 [OKT10]-PE

2018 July 13

Zika convalescent macaques display delayed induction of anamnestic cross-neutralizing antibody responses after dengue infection.

Valiant, William G; Huang, Yan-Jang S; Vanlandingham, Dana L; Higgs, Stephen; Lewis, Mark G; Mattapallil, Joseph J

Emerging Microbes & Infections

Legacy Product

2018 June 01

HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition.

Vaccari, Monica; Fourati, Slim; Gordon, Shari N; Brown, Dallas R; Bissa, Massimilano; Schifanella, Luca; Silva de Castro, Isabela; Doster, Melvin N; Galli, Veronica; Omsland, Maria; Fujikawa, Dai; Gorini, Giacomo; Liyanage, Namal P M; Trinh, Hung V; McKinnon, Katherine M; Foulds, Kathryn E; Keele, Brandon F; Roederer, Mario; Koup, Richard A; Shen, Xiaoying; Tomaras, Georgia D; Wong, Marcus P; Munoz, Karissa J; Gach, Johannes S; Forthal, Donald N; Montefiori, David C; Venzon, David J; Felber, Barbara K; Rosati, Margherita; Pavlakis, George N; Rao, Mangala; Sekaly, Rafick-Pierre; Franchini, Genoveffa

Nature Medicine

Anti-alpha4/beta7 [A4B7R1]-APC

2018 May 11

Temporal/compartmental changes in viral RNA and neuronal injury in a primate model of NeuroAIDS.

González, R Gilberto; Fell, Robert; He, Julian; Campbell, Jennifer; Burdo, Tricia H; Autissier, Patrick; Annamalai, Lakshmanan; Taheri, Faramarz; Parker, Termara; Lifson, Jeffrey D; Halpern, Elkan F; Vangel, Mark; Masliah, Eliezer; Westmoreland, Susan V; Williams, Kenneth C; Ratai, Eva-Maria

PloS One

Anti-CD8 alpha [MT807R1]

2018 May 01

Early treatment of SIV+ macaques with analpha4/beta7 alters virus distribution and preserves CD4+ T cells in later stages of infection.

Santangelo, P J; Cicala, C; Byrareddy, S N; Ortiz, K T; Little, D; Lindsay, K E; Gumber, S; Hong, J J; Jelicic, K; Rogers, K A; Zurla, C; Villinger, F; Ansari, A A; Fauci, A S; Arthos, J

Mucosal Immunology

Anti-alpha4/beta7 [A4B7R1] Control antibody rhesus IgG1 (anti-DSP) [DSPR1] Anti-CD4 [OKT4]

2018 April 15

Associations of Simian Immunodeficiency Virus (SIV)-Specific Follicular CD8+ T Cells with Other Follicular T Cells Suggest Complex Contributions to SIV Viremia Control.

Rahman, Mohammad Arif; McKinnon, Katherine M; Karpova, Tatiana S; Ball, David A; Venzon, David J; Fan, Wenjin; Kang, Guobin; Li, Qingsheng; Robert-Guroff, Marjorie

Journal of Immunology (Baltimore, Md. : 1950)

Anti-CXCR5 [710D82.1]-PE

2018 April 05

Emerging diagnostic challenges and characteristics of simian betaretrovirus infections in captive macaque colonies.

Yee JL, Grant R, Van Rompay KK, Kuller L, Carpenter A, Watanabe R, Huebner R, Agricola B, Smedley J, Roberts JA

Journal of medical primatology

Anti-CD8 alpha [MT807R1]

2018 April 01

Long-term Nonhuman Primate Renal Allograft Survival Without Ongoing Immunosuppression in Recipients of Delayed Donor Bone Marrow Transplantation.

Hotta, Kiyohiko; Oura, Tetsu; Dehnadi, Abbas; Boskovic, Svjetlan; Matsunami, Masatoshi; Rosales, Ivy; Smith, Rex N; Colvin, Robert B; Cosimi, A Benedict; Kawai, Tatsuo

Transplantation

Legacy Product

2018 March 28

Simian Varicella Virus Infects Enteric Neurons andalpha4/beta7 Integrin-Expressing Gut-Tropic T-Cells in Nonhuman Primates.

Ouwendijk, Werner J D; Van Veen, Suzanne; Mehraban, Tamana; Mahalingam, Ravi; Verjans, Georges M G M

Viruses

Anti-alpha4/beta7 [A4B7R1]-APC Anti-alpha4/beta7 [A4B7R1]-PE

2018 March 20

Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication.

Haran, Kumudhini Preethi; Hajduczki, Agnes; Pampusch, Mary S; Mwakalundwa, Gwantwa; Vargas-Inchaustegui, Diego A; Rakasz, Eva G; Connick, Elizabeth; Berger, Edward A; Skinner, Pamela J

Frontiers in Immunology

Anti-CD28 [CD28.2] Anti-CD3 [FN18]

2018 March 01

Selective CD28 Inhibition Modulates Alloimmunity and Cardiac Allograft Vasculopathy in Anti-CD154-Treated Monkeys.

Zhang, Tianshu; Azimzadeh, Agnes M; Sun, Wenji; O'neill, Natalie A; Sievert, Evelyn; Bergbower, Emily; Braileanu, Gheorghe; Burdorf, Lars; Cheng, Xiangfei; Monahan, Thomas; Dahi, Siamak; Harris, Donald G; Rybak, Elana; Welty, Emily; Kronfli, Anthony; Avon, Chris; Pierson, Richard N

Transplantation

Legacy Product

2018 February 16

Thrombalexin: Use of a Cytotopic Anticoagulant to Reduce Thrombotic Microangiopathy in a Highly Sensitized Model of Kidney Transplantation.

Manook M, Kwun J, Burghuber C, Samy K, Mulvihill M, Yoon J, Xu H, MacDonald AL, Freischlag K, Curfman V, Branum E, Howell D, Farris AB, Smith RA, Sacks S, Dorling A, Mamode N, Knechtle SJ

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Anti-CD8 alpha [MT807R1]

2018 February 02

Pilot Study of Delayed ICOS/ICOS-L Blockade With αCD40 to Modulate Pathogenic Alloimmunity in a Primate Cardiac Allograft Model.

O'neill, Natalie A; Zhang, Tianshu; Braileanu, Gheorghe; Cheng, Xiangfei; Hershfeld, Alena; Sun, Wenji; Reimann, Keith A; Dahi, Sia; Kubicki, Natalia; Hassanein, Wessam; Laird, Christopher; Cimeno, Arielle; Azimzadeh, Agnes M; Pierson, Richard N

Transplantation Direct

Anti-CD40 [2C10R4] Anti-MHC-class I [W6/32]

2018 January 15

Integrinalpha4/beta7 Blockade Preferentially Impacts CCR6+ Lymphocyte Subsets in Blood and Mucosal Tissues of Naive Rhesus Macaques.

Calenda, Giulia; Keawvichit, Rassamon; Arrode-Brusés, Géraldine; Pattanapanyasat, Kovit; Frank, Ines; Byrareddy, Siddappa N; Arthos, James; Cicala, Claudia; Grasperge, Brooke; Blanchard, James L; Gettie, Agegnehu; Reimann, Keith A; Ansari, Aftab A; Martinelli, Elena

Journal of Immunology (Baltimore, Md. : 1950)

Legacy Product Anti-alpha4/beta7 [A4B7R1] Anti-alpha4/beta7 [A4B7R1]-PE

2018 January 10

Optimization and comparison of CD4-targeting lipid-polymer hybrid nanoparticles using different binding ligands.

Cao, Shijie; Jiang, Yonghou; Levy, Claire N; Hughes, Sean M; Zhang, Hangyu; Hladik, Florian; Woodrow, Kim A

Journal of Biomedical Materials Research. Part A

Anti-CD4 [CD4R1] Control antibody rhesus IgG1 (anti-DSP) [DSPR1]

2018 January 10

Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques.

Eudailey, Joshua A; Dennis, Maria L; Parker, Morgan E; Phillips, Bonnie L; Huffman, Tori N; Bay, Camden P; Hudgens, Michael G; Wiseman, Roger W; Pollara, Justin J; Fouda, Genevieve G; Ferrari, Guido; Pickup, David J; Kozlowski, Pamela A; Van Rompay, Koen K A; De Paris, Kristina; Permar, Sallie R

MSphere

Anti-rhesus IgA [10F12]-biotin

2018 January 01

Pre-clinical results in pig-to-non-human primate islet xenotransplantation using anti-CD40 antibody (2C10R4)-based immunosuppression.

Shin, Jun-Seop; Kim, Jong-Min; Min, Byoung-Hoon; Yoon, Il Hee; Kim, Hyun Je; Kim, Jung-Sik; Kim, Yong-Hee; Kang, Seong-Jun; Kim, Jiyeon; Kang, Hee-Jung; Lim, Dong-Gyun; Hwang, Eung-Soo; Ha, Jongwon; Kim, Sang-Joon; Park, Wan Beom; Park, Chung-Gyu

Xenotransplantation

Anti-CD40 [2C10R4]

2018 January 01

Delayed revascularization of islets after transplantation by IL-6 blockade in pig to non-human primate islet xenotransplantation model.

Min, Byoung-Hoon; Shin, Jun-Seop; Kim, Jong-Min; Kang, Seong-Jun; Kim, Hyun-Je; Yoon, Il-Hee; Park, Su-Kyoung; Choi, Ji-Won; Lee, Min-Suk; Park, Chung-Gyu

Xenotransplantation

Anti-CD40 [2C10R4]

2018 January 01

The Role of MHC-E in T Cell Immunity Is Conserved among Humans, Rhesus Macaques, and Cynomolgus Macaques.

Wu, Helen L; Wiseman, Roger W; Hughes, Colette M; Webb, Gabriela M; Abdulhaqq, Shaheed A; Bimber, Benjamin N; Hammond, Katherine B; Reed, Jason S; Gao, Lina; Burwitz, Benjamin J; Greene, Justin M; Ferrer, Fidel; Legasse, Alfred W; Axthelm, Michael K; Park, Byung S; Brackenridge, Simon; Maness, Nicholas J; McMichael, Andrew J; Picker, Louis J; O'connor, David H; Hansen, Scott G; Sacha, Jonah B

Journal of Immunology (Baltimore, Md. : 1950)

Anti-Mamu A*01 [P12]-PE

2017 December 05

Experimental Oral Herpes Simplex Virus-1 (HSV-1) Co-infection in Simian Immunodeficiency Virus (SIV)-Infected Rhesus Macaques.

Aravantinou, Meropi; Mizenina, Olga; Calenda, Giulia; Kenney, Jessica; Frank, Ines; Lifson, Jeffrey D; Szpara, Moriah; Jing, Lichen; Koelle, David M; Teleshova, Natalia; Grasperge, Brooke; Blanchard, James; Gettie, Agegnehu; Martinelli, Elena; Derby, Nina

Frontiers in Microbiology

Anti-alpha4/beta7 [A4B7R1]-APC

2017 November 13

Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice.

Li X, Huang J, Zhang M, Funakoshi R, Sheetij D, Spaccapelo R, Crisanti A, Nussenzweig V, Nussenzweig RS, Tsuji M

Vaccine

Control antibody rhesus IgG1 (anti-DSP) [DSPR1] Anti-CD8 alpha [MT807R1]

2017 November 10

Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgus macaques recapitulates diverse human clinical outcomes.

Burwitz, Benjamin J; Wu, Helen L; Abdulhaqq, Shaheed; Shriver-Munsch, Christine; Swanson, Tonya; Legasse, Alfred W; Hammond, Katherine B; Junell, Stephanie L; Reed, Jason S; Bimber, Benjamin N; Greene, Justin M; Webb, Gabriela M; Northrup, Mina; Laub, Wolfram; Kievit, Paul; MacAllister, Rhonda; Axthelm, Michael K; Ducore, Rebecca; Lewis, Anne; Colgin, Lois M A; Hobbs, Theodore; Martin, Lauren D; Ferguson, Betsy; Thomas, Charles R; Panoskaltsis-Mortari, Angela; Meyers, Gabrielle; Stanton, Jeffrey J; Maziarz, Richard T; Sacha, Jonah B

Nature Communications

Legacy Product

2017 November 09

CD4+ levels control the odds of induction of humoral immune responses to tracer doses of therapeutic antibodies.

Srinivasula, Sharat; Gabriel, Erin; Kim, Insook; DeGrange, Paula; St Claire, Alexis; Mallow, Candace; Donahue, Robert E; Paik, Chang; Lane, H C; Di Mascio, Michele

PloS One

Anti-CD4 [CD4R1] Anti-CD4 [OKT4]

2017 November 01

Persistent accumulation of gut macrophages with impaired phagocytic function correlates with SIV disease progression in macaques.

Swan, Zachary D; Bouwer, Anthea L; Wonderlich, Elizabeth R; Barratt-Boyes, Simon M

European Journal of Immunology

Anti-alpha4/beta7 [A4B7R1]-APC Anti-alpha4/beta7 [A4B7R1]-PE

2017 November 01

Phenotypic and Functional Characterization of Circulatory, Splenic, and Hepatic NK Cells in Simian Immunodeficiency Virus-Controlling Macaques.

Vargas-Inchaustegui, Diego A; Helmold Hait, Sabrina; Chung, Hye Kyung; Narola, Jigna; Hoang, Tanya; Robert-Guroff, Marjorie

Journal of Immunology (Baltimore, Md. : 1950)

Legacy Product

2017 November 01

Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys.

Huot, Nicolas; Jacquelin, Beatrice; Garcia-Tellez, Thalia; Rascle, Philippe; Ploquin, Mickaël J; Madec, Yoann; Reeves, R Keith; Derreudre-Bosquet, Nathalie; Müller-Trutwin, Michaela

Nature Medicine

Anti-IL-15 [IL-15R1LALA]

2017 October 26

Pegivirus avoids immune recognition but does not attenuate acute-phase disease in a macaque model of HIV infection.

Bailey, Adam L; Buechler, Connor R; Matson, Daniel R; Peterson, Eric J; Brunner, Kevin G; Mohns, Mariel S; Breitbach, Meghan; Stewart, Laurel M; Ericsen, Adam J; Newman, Christina M; Koenig, Michelle R; Mohr, Emma; Tan, John; Capuano, Saverio; Simmons, Heather A; Yang, David T; O'connor, David H

PloS Pathogens

Anti-primate IgG [8F1]-biotin

2017 October 01

Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates

Jean Kwun, Christopher Burghuber, Miriam Manook, Brian Ezekian, Jaeberm Park, Janghoon Yoon, John S Yi, Neal Iwakoshi, Adriana Gibby, Jung Joo Hong, Alton B Farris, Allan D Kirk, Stuart J Knechtle

Blood Adv

Anti-CD40 [2C10R4]

2017 October 01

An Investigation of Extracellular Histones in Pig-To-Baboon Organ Xenotransplantation.

Li, Tao; Lee, Whayoung; Hara, Hidetaka; Long, Cassandra; Ezzelarab, Mohamed; Ayares, David; Huang, Hai; Wang, Yi; Esmon, Charles T; Cooper, David K C; Iwase, Hayato

Transplantation

Anti-CD40 [2C10R4] Anti-CD154 [5C8H1]

2017 September 05

CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.

Cartwright EK, Spicer L, Smith SA, Lee D, Fast R, Paganini S, Lawson BO, Nega M, Easley K, Schmitz JE, Bosinger SE, Paiardini M, Chahroudi A, Vanderford TH, Estes JD, Lifson JD, Derdeyn CA, Silvestri G

Immunity

Anti-CD8 alpha [MT807R1]

2017 September 01

Comparative Evaluation of αCD40 (2C10R4) and αCD154 (5C8H1 and IDEC-131) in a Nonhuman Primate Cardiac Allotransplant Model.

OʼNeill, Natalie A; Zhang, Tianshu; Braileanu, Gheorghe; Sun, Wenji; Cheng, Xiangfei; Hershfeld, Alena; Laird, Christopher T; Kronfli, Anthony; Hock, Lindsay A; Dahi, Siamak; Kubicki, Natalia; Sievert, Evelyn; Hassanein, Wessam; Cimeno, Arielle; Pierson, Richard N; Azimzadeh, Agnes M

Transplantation

Anti-CD40 [2C10R4] Anti-CD154 [5C8H1]

2017 August 17

HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy.

Gupta, Manish K; Kaminski, Rafal; Mullen, Brian; Gordon, Jennifer; Burdo, Tricia H; Cheung, Joseph Y; Feldman, Arthur M; Madesh, Muniswamy; Khalili, Kamel

Scientific Reports

Anti-CD8 alpha [MT807R1]

2017 August 01

Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade.

Shah, J A; Patel, M S; Elias, N; Navarro-Alvarez, N; Rosales, I; Wilkinson, R A; Louras, N J; Hertl, M; Fishman, J A; Colvin, R B; Cosimi, A B; Markmann, J F; Sachs, D H; Vagefi, P A

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Anti-CD40 [2C10R4]

2017 August 01

An oral form of methylglyoxal-bis-guanylhydrazone reduces monocyte activation and traffic to the dorsal root ganglia in a primate model of HIV-peripheral neuropathy.

Lakritz, Jessica R; Yalamanchili, Samshita; Polydefkis, Michael J; Miller, Andrew D; McGrath, Michael S; Williams, Kenneth C; Burdo, Tricia H

Journal of Neurovirology

Anti-CD8 alpha [MT807R1]

2017 July 18

Isolation of a monoclonal antibody from a phage display library binding the rhesus macaque MHC class I allomorph Mamu-A1*001.

Holman, Nathan; Weinfurter, Jason T; Harsla, Trevor R; Wiseman, Roger W; Belli, Aaron J; Michaels, Anthony J; Reimann, Keith A; DeMars, Robert I; Reynolds, Matthew R

PloS One

Anti-rhesus IgG1/3 [1B3]-FITC Anti-Mamu A*01 [P12]-PE

2017 July 14

KIR3DL01 upregulation on gut natural killer cells in response to SIV infection of KIR- and MHC class I-defined rhesus macaques.

Ries, Moritz; Reynolds, Matthew R; Bashkueva, Ksenia; Crosno, Kristin; Capuano, Saverio; Prall, Trent M; Wiseman, Roger; O'connor, David H; Rakasz, Eva G; Uno, Hajime; Lifson, Jeffrey D; Evans, David T

PloS Pathogens

Anti-alpha4/beta7 [A4B7R1]-APC

2017 July 01

Humoral Compensation after Bortezomib Treatment of Allosensitized Recipients

Jean Kwun, Christopher Burghuber, Miriam Manook, Neal Iwakoshi, Adriana Gibby, Jung Joo Hong, Stuart Knechtle

J Am Soc Nephrol

Anti-CD38 [OKT10]-APC

2017 June 27

Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells.

Bolton, Diane L; McGinnis, Kathleen; Finak, Greg; Chattopadhyay, Pratip; Gottardo, Raphael; Roederer, Mario

PloS Pathogens

Anti-CD38 [OKT10]-PE

2017 June 23

Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers.

Policicchio BB, Xu C, Brocca-Cofano E, Raehtz KD, He T, Ma D, Li H, Sivanandham R, Haret-Richter GS, Dunsmore T, Trichel A, Mellors JW, Hahn BH, Shaw GM, Ribeiro RM, Pandrea I, Apetrei C

PLoS pathogens

Anti-CD8 alpha [MT807R1]

2017 June 01

Characteristics of HIV target CD4 T cells collected using different sampling methods from the genital tract of HIV seronegative women.

Iyer, Smita S; Sabula, Michael J; Mehta, C Christina; Haddad, Lisa B; Brown, Nakita L; Amara, Rama R; Ofotokun, Igho; Sheth, Anandi N

PloS One

Anti-alpha4/beta7 [A4B7R1]-APC Anti-alpha4/beta7 [A4B7R1]-PE

2017 May 01

Anti-CD40 antibody-mediated costimulation blockade promotes long-term survival of deep-lamellar porcine corneal grafts in non-human primates.

Kim, Jaeyoung; Kim, Dong Hyun; Choi, Hyuk Jin; Lee, Hyun Ju; Kang, Hee Jung; Park, Chung-Gyu; Hwang, Eung-Soo; Kim, Mee Kum; Wee, Won Ryang

Xenotransplantation

Anti-CD40 [2C10R4]

2017 May 01

Selective Targeting of High-Affinity LFA-1 Does Not Augment Costimulation Blockade in a Nonhuman Primate Renal Transplantation Model.

Samy, K P; Anderson, D J; Lo, D J; Mulvihill, M S; Song, M; Farris, A B; Parker, B S; MacDonald, A L; Lu, C; Springer, T A; Kachlany, S C; Reimann, K A; How, T; Leopardi, F V; Franke, K S; Williams, K D; Collins, B H; Kirk, A D

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Legacy Product

2017 March 23

Early antibody therapy can induce long-lasting immunity to SHIV.

Nishimura, Yoshiaki; Gautam, Rajeev; Chun, Tae-Wook; Sadjadpour, Reza; Foulds, Kathryn E; Shingai, Masashi; Klein, Florian; Gazumyan, Anna; Golijanin, Jovana; Donaldson, Mitzi; Donau, Olivia K; Plishka, Ronald J; Buckler-White, Alicia; Seaman, Michael S; Lifson, Jeffrey D; Koup, Richard A; Fauci, Anthony S; Nussenzweig, Michel C; Martin, Malcolm A

Nature

Anti-CD8 beta [CD8b255R1] Anti-CD8 alpha [MT807R1]

2017 March 13

Rhesus macaque and mouse models for down-selecting circumsporozoite protein based malaria vaccines differ significantly in immunogenicity and functional outcomes.

Phares, Timothy W; May, Anthony D; Genito, Christopher J; Hoyt, Nathan A; Khan, Farhat A; Porter, Michael D; DeBot, Margot; Waters, Norman C; Saudan, Philippe; Dutta, Sheetij

Malaria Journal

Anti-rhesus IgG1 [ena]-HRP - in production Legacy Product

2017 March 07

Differential induction of anti-V3 crown antibodies with cradle- and ladle-binding modes in response to HIV-1 envelope vaccination.

Balasubramanian, Preetha; Kumar, Rajnish; Williams, Constance; Itri, Vincenza; Wang, Shixia; Lu, Shan; Hessell, Ann J; Haigwood, Nancy L; Sinangil, Faruk; Higgins, Keith W; Liu, Lily; Li, Liuzhe; Nyambi, Phillipe; Gorny, Miroslaw K; Totrov, Maxim; Nadas, Arthur; Kong, Xiang-Peng; Zolla-Pazner, Susan; Hioe, Catarina E

Vaccine

Legacy Product

2017 March 01

Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates.

Gori, Jennifer L; Butler, Jason M; Kunar, Balvir; Poulos, Michael G; Ginsberg, Michael; Nolan, Daniel J; Norgaard, Zachary K; Adair, Jennifer E; Rafii, Shahin; Kiem, Hans-Peter

Stem Cells Translational Medicine

Anti-CD38 [OKT10]-APC

2017 March 01

Transplantation of hepatocytes from genetically engineered pigs into baboons.

Iwase, Hayato; Liu, Hong; Schmelzer, Eva; Ezzelarab, Mohamed; Wijkstrom, Martin; Hara, Hidetaka; Lee, Whayoung; Singh, Jagjit; Long, Cassandra; Lagasse, Eric; Gerlach, Jörg C; Cooper, David K C; Gridelli, Bruno

Xenotransplantation

Anti-CD40 [2C10R4]

2017 March 01

Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts.

Iwase, Hayato; Hara, Hidetaka; Ezzelarab, Mohamed; Li, Tao; Zhang, Zhongqiang; Gao, Bingsi; Liu, Hong; Long, Cassandra; Wang, Yi; Cassano, Amy; Klein, Edwin; Phelps, Carol; Ayares, David; Humar, Abhinav; Wijkstrom, Martin; Cooper, David K C

Xenotransplantation

Anti-CD40 [2C10R4]

2017 March 01

Therapeutic regulation of systemic inflammation in xenograft recipients.

Iwase, Hayato; Liu, Hong; Li, Tao; Zhang, Zhongquiang; Gao, Bingsi; Hara, Hidetaka; Wijkstrom, Martin; Long, Cassandra; Saari, Ryan; Ayares, David; Cooper, David K C; Ezzelarab, Mohamed B

Xenotransplantation

Anti-CD40 [2C10R4]

2017 March 01

Immunosuppression With CD40 Costimulatory Blockade Plus Rapamycin for Simultaneous Islet-Kidney Transplantation in Nonhuman Primates.

Oura, T; Hotta, K; Lei, J; Markmann, J; Rosales, I; Dehnadi, A; Kawai, K; Ndishabandi, D; Smith, R-N; Cosimi, A B; Kawai, T

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Legacy Product Anti-CD40 [2C10R4]

2017 February 21

Pre-existing neutralizing antibody mitigates B cell dysregulation and enhances the Env-specific antibody response in SHIV-infected rhesus macaques.

Jaworski, Juan Pablo; Bryk, Peter; Brower, Zachary; Zheng, Bo; Hessell, Ann J; Rosenberg, Alexander F; Wu, Tong Tong; Sanz, Ignacio; Keefer, Michael C; Haigwood, Nancy L; Kobie, James J

PloS One

Anti-CD38 [OKT10]-APC

2017 January 01

Safe use of anti-CD154 monoclonal antibody in pig islet xenotransplantation in monkeys.

Bottino, Rita; Knoll, Michael F; Graeme-Wilson, Joshua; Klein, Edwin C; Ayares, David; Trucco, Massimo; Cooper, David K C

Xenotransplantation

Legacy Product

2017 January 01

Tolerance of Vascularized Islet-Kidney Transplants in Rhesus Monkeys.

Pathiraja, V; Villani, V; Tasaki, M; Matar, A J; Duran-Struuck, R; Yamada, R; Moran, S G; Clayman, E S; Hanekamp, J; Shimizu, A; Sachs, D H; Huang, C A; Yamada, K

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Legacy Product

2017 January 01

Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization.

Fouda, Genevieve G; Eudailey, Joshua; Kunz, Erika L; Amos, Joshua D; Liebl, Brooke E; Himes, Jonathan; Boakye-Agyeman, Felix; Beck, Krista; Michaels, Anthony J; Cohen-Wolkowiez, Michael; Haynes, Barton F; Reimann, Keith A; Permar, Sallie R

Mucosal Immunology

Legacy Product

2016 December 30

Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques.

Roberts, Emily R; Carnathan, Diane G; Li, Hui; Shaw, George M; Silvestri, Guido; Betts, Michael R

PloS Pathogens

Anti-CD38 [OKT10]-PE

2016 December 15

Mucosal and Systemic γδ+ T Cells Associated with Control of Simian Immunodeficiency Virus Infection.

Tuero, Iskra; Venzon, David; Robert-Guroff, Marjorie

Journal of Immunology (Baltimore, Md. : 1950)

Anti-alpha4/beta7 [A4B7R1]-APC

2016 December 13

Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses.

Boesch, Austin W; Osei-Owusu, Nana Yaw; Crowley, Andrew R; Chu, Thach H; Chan, Ying N; Weiner, Joshua A; Bharadwaj, Pranay; Hards, Rufus; Adamo, Mark E; Gerber, Scott A; Cocklin, Sarah L; Schmitz, Joern E; Miles, Adam R; Eckman, Joshua W; Belli, Aaron J; Reimann, Keith A; Ackerman, Margaret E

Frontiers in Immunology

Legacy Product

2016 December 01

Zika viral dynamics and shedding in rhesus and cynomolgus macaques.

Osuna, Christa E; Lim, So-Yon; Deleage, Claire; Griffin, Bryan D; Stein, Derek; Schroeder, Lukas T; Omange, Robert Were; Best, Katharine; Luo, Ma; Hraber, Peter T; Andersen-Elyard, Hanne; Ojeda, Erwing Fabian Cardozo; Huang, Scott; Vanlandingham, Dana L; Higgs, Stephen; Perelson, Alan S; Estes, Jacob D; Safronetz, David; Lewis, Mark G; Whitney, James B

Nature Medicine

Legacy Product

2016 December 01

Breadth and magnitude of antigen-specific antibody responses in the control of plasma viremia in simian immunodeficiency virus infected macaques.

Pahar, Bapi; Kenway-Lynch, Carys S; Marx, Preston; Srivastav, Sudesh K; LaBranche, Celia; Montefiori, David C; Das, Arpita

Virology Journal

Legacy Product

2016 November 01

High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.

Kannanganat, Sunil; Wyatt, Linda S; Gangadhara, Sailaja; Chamcha, Venkatesarlu; Chea, Lynette S; Kozlowski, Pamela A; LaBranche, Celia C; Chennareddi, Lakshmi; Lawson, Benton; Reddy, Pradeep B J; Styles, Tiffany M; Vanderford, Thomas H; Montefiori, David C; Moss, Bernard; Robinson, Harriet L; Amara, Rama Rao

Journal of Immunology (Baltimore, Md. : 1950)

Anti-alpha4/beta7 [A4B7R1]-PE

2016 November 01

Prevention of SHIV transmission by topical IFN-β treatment.

Veazey, R S; Pilch-Cooper, H A; Hope, T J; Alter, G; Carias, A M; Sips, M; Wang, X; Rodriguez, B; Sieg, S F; Reich, A; Wilkinson, P; Cameron, M J; Lederman, M M

Mucosal Immunology

Legacy Product

2016 November 01

Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques.

Negri, Donatella; Blasi, Maria; LaBranche, Celia; Parks, Robert; Balachandran, Harikrishnan; Lifton, Michelle; Shen, Xiaoying; Denny, Thomas; Ferrari, Guido; Vescio, Maria Fenicia; Andersen, Hanne; Montefiori, David C; Tomaras, Georgia D; Liao, Hua-Xin; Santra, Sampa; Haynes, Barton F; Klotman, Mary E; Cara, Andrea

Molecular Therapy : the Journal of the American Society of Gene Therapy

Reference rhesus dimeric IgA [b12rA1d] Reference rhesus monomeric IgA [b12rA1m] Legacy Product

2016 October 23

Reproducing SIVΔnef vaccine correlates of protection: trimeric gp41 antibody concentrated at mucosal front lines.

Voss, James E; Macauley, Matthew S; Rogers, Kenneth A; Villinger, Francois; Duan, Lijie; Shang, Liang; Fink, Elizabeth A; Andrabi, Raiees; Colantonio, Arnaud D; Robinson, James E; Johnson, R Paul; Burton, Dennis R; Haase, Ashley T

AIDS (London, England)

Legacy Product

2016 October 12

A Single Nucleotide Polymorphism in Human APOBEC3C Enhances Restriction of Lentiviruses.

Wittkopp, Cristina J; Adolph, Madison B; Wu, Lily I; Chelico, Linda; Emerman, Michael

PloS Pathogens

Sabaeus B-lymphoblastoid cell line [V038 AGM BLCL]

2016 October 07

Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection.

Miles, Brodie; Miller, Shannon M; Folkvord, Joy M; Levy, David N; Rakasz, Eva G; Skinner, Pamela J; Connick, Elizabeth

PloS Pathogens

Anti-CXCR5 [710D82.1]
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