No, you do not need to register to use our site. Anyone using our site is able to:

• Submit a suggestion for a new reagent
• Share published articles that mention our reagents
• View, sort and filter our database of reagents

However if you wish to purchase products or experience advanced features, 

The following functions are available for those who are registered eligible users:

EVERYONE

View user-contributed information on the Reactivity Database

Submit species reactivity & information to the Reactivity Database

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NON-PI RESEARCHERS

View user-contributed information on the Reactivity Database

Submit species reactivity & information to the Reactivity Database

Ability to purchase our products, includes third-party payment option

View order status under My Account

Requirements:

1. Must work under a registered PI

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PRINCIPAL INVESTIGATOR

View user-contributed information on the Reactivity Database

Submit species reactivity & information to the Reactivity Database

Ability to purchase our products, includes third-party payment option

View order status under My Account

Requirements:

1. Must meet purchase eligibility
2. Must complete application process, which includes having a signed contract with us.

REGISTER NOW

To purchase from the NIH Nonhuman Primate Reagent Resource, you must have a valid contract signed by your institution and a Principal Investigator, Laboratory Director, or equivalent (public or academic institution), or a Director of Research or equivalent (private or for-profit institution).

A Principal Investigator, Laboratory Director, or equivalent (public or academic institution), or a Director of Research or equivalent (private or for-profit institution) must complete and submit a registration form. These can be entirely completed online and digitally signed, or the contract can be emailed back to us. Two signatures are required -- one from the PI or equivalent, plus one from a Signing Official with legal authority to represent the organization. Don't forget to log in! After approval, you need to be logged into an approved account to purchase reagents. If you're not logged into an approved account, you'll see the message: 'Your account is not authorized to purchase this item'.

Academic or commercial investigators may register to order reagents from the NHP Reagent Resource. In the event that supplies are limited, preference will be given to NIH-funded investigators. However, funding from the NIH is not a requirement for participation. Distributors are not permitted under any circumstances. Registration for international organizations will be evaluated on a case-by-case basis.

Registration in the NHP Reagent Resource program is required to receive reagents. The registration form is available online here (you can also download and fill it offline). We have attempted to provide as many materials as possible solely under the terms of this agreement. However, some reagents obtained through the ATCC or from some companies may require an additional MTAs. This requirement is disclosed in the description of each reagent. We will advise you of this requirement when the order is placed or you can submit a request for more information here.

For reagents provided at no cost, two units (typically 100 tests or 1 mg) can be provided per year. If larger amounts are needed, please contact us to explain your need and approval from NIH program officials will be requested. There are no limits on reagents for in vivo administration that are subject to cost recovery.

At the time of registration, we require you to provide a courier service account number that can be billed for shipping charges. We typically ship via FedEx and UPS domestically, FedEx and World Courier for international shipments. We will do our best to accommodate your preferred courier. Requesters are required to pay all shipping costs by establishing an account with an overnight shipping company, preferably Federal Express, and providing their account number to the NIH Nonhuman Primate Reagent Resource. Unless otherwise requested, shipments are made using standard overnight delivery.

We require a purchase order number for all orders where costs are recovered. For international shipments, we prefer wire transfer payment. Questions on payment methods can be asked here.

We can ship most reagents internationally. However, export of biological specimens obtained from nonhuman primates is regulated by the Convention on International Trade in Endangered Species (CITES). Therefore, with few exceptions, biological specimens such as cell lines cannot be shipped internationally.

The Nonhuman Primate Reagent Resource (NHPRR) is an NIH-supported program dedicated to developing, producing, and distributing immune reagents specifically optimized for use in nonhuman primates (NHPs)—such as rhesus and cynomolgus macaques. These models are essential for translational research in immunology, infectious disease, transplantation, and more. One of NHPRR’s key roles is to support the development of therapeutic-grade antibody reagents specifically designed and manufactured for infusion into nonhuman primates (NHPs).

NHPRR’s mission is to fill critical gaps where human or murine reagents do not work reliably in NHP studies. This includes creating species cross-reactive antibodies, recombinant proteins, and tools that enhance the reproducibility and interpretability of NHP research.

Unlike other NIH-funded reagent programs—such as the BEI Resources (for infectious disease reagents) or the HIV Reagent Program—NHPRR is:
    •    Model-specific, not pathogen-specific
    •    Focused on NHP biology, not infectious disease agents
    •    Collaborative with investigators to develop custom or unmet-need reagents
    •    Committed to maintaining and characterizing reagents that are validated for NHP use
    •    Produce and maintain infusion-grade experimental reagents under a quality system designed to support safe and effective administration in animal studies

If you’re working with nonhuman primate models, NHPRR is your go-to resource for tools that work in those systems. For pathogens or general human research reagents, you may want to explore other programs like BEI Resources or ATCC.

For more information, contact us at nhprr@umassmed.edu. 

All reagents listed in the Resource Reagents section are in stock and available unless otherwise noted. If you anticipate needing an unusually large amount of a particular reagent, we would appreciate know this before you place the first order so production can be planned to keep it in stock.

None of the reagents provided have been approved for in vitro diagnostics of human or for use in humans. Other restrictions on reagent use are described in the registration agreement shown here. Those reagents that require MTAs may have additional restrictions.

We request that any manuscripts resulting from the use of these Reagent Resource materials please acknowledge these contributions. We use reagent identifiers (scicrunch.org) to facilitate proper antibody identification.

Citation Example (how to cite using RRIDs): 

For your Materials & Methods section:
The Anti-CD8 alpha [MT807R1] antibody (Cat#PR-0817, RRID:AB_2716320) was engineered and produced by the Nonhuman Primate Reagent Resource (NHPRR, RRID:SCR_012986).

For your Acknowledgements  section:

The Anti-CD8 alpha [MT807R1] antibody (Cat#PR-0817, RRID:AB_2716320) used in this study was provided by the Nonhuman Primate Reagent Resource (NHPRR, RRID:SCR_012986), funded by ORIP P40 OD028116.

All antibody and fusion protein reagents are produced by cell culture or in bioreactors using serum-free medium. Antibodies and Ig-fusion proteins are purified by affinity chromatography. Prior to release, reagents for in vivo administration are tested for bioburden, endotoxin, purity, specificity, and pH. Each shipment includes a certificate of analysis describing the results of these release criteria. Please contact us if you have questions about the manufacture of any particular reagents.

Most IACUCs are concerned that the materials being administered to animals have been properly prepared and do not have significant toxicities. You may explain that all materials have been produced and purified under aseptic conditions. Sterility, purity and endotoxin levels are all measured before release. All have been tested in animals and shown to result in no untoward effects.

If reference to our website is insufficient to confirm the availability of a specific reagent, please contact us to obtain a letter of support.

Suggestions for new reagents can be made online at this link.

All data contained in the Commercial Antibody Database were contributed by investigators or by product manufacturers/distributors. We do not confirm these results. If conflicting results are provided for a particular antibody clone, we may test these in our laboratory.

Contributions of data may be made here or by attaching spreadsheets to an email sent to us.

If you believe results in the database are in error, please contact us and we will try to resolve the discrepancy.