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Anti-alpha4/beta7 [A4B7R1]

Anti-alpha4/beta7 [A4B7R1]
Product Type: Therapeutics (In Vivo)
Format: Anti-alpha-4/beta-7 integrin, humanized variable region, rhesus IgG1LAGA Fc
Clone ID: A4B7R1
RRID: AB_2716326
Common Names: Anti-alpha4/beta7 [A4B7R1] | Anti-alpha-4/beta-7 integrin | pACT1 | vedolizumab | Anti-Alpha-4/beta-7 | PR-1427 | NHP16
Target: Alpha4/beta7
Reactivity: Rhesus Macaque (Macaca mulatta) Human (Homo sapiens)
Applications: in vivo
Description:

A4B7R1LAGA: Rhesus recombinant, humanized anti-alpha4beta7, effector-silenced IgG1-kappa antibody. Derived from vedolizumab.

 

How to cite this reagent:

The rhesus IgG1 recombinant Anti-alpha4/beta7 [A4B7R1] monoclonal antibody was engineered with 'LAGA' mutations and produced by the Nonhuman Primate Reagent Resource (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)
Modifications: None
Restrictions: No
Sponsor: NIAID
How to cite (Methods): "The rhesus IgG1 recombinant Anti-alpha4/beta7 [A4B7R1] monoclonal antibody was engineered with 'LAGA' mutations and produced by the Nonhuman Primate Reagent Resource (NIH Nonhuman Primate Reagent Resource Cat# PR-1427, RRID:AB_2716326)."
How to cite (Acknowledgments): "The Anti-alpha4/beta7 [A4B7R1] antibody used in this study was provided by the NIH Nonhuman Primate Reagent Resource (U24 AI126683)"

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The Nonhuman Primate Reagent Resource (NHPRR) is a nonprofit laboratory established in 1999, and supported by the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), and Office of Research Infrastructure Programs (ORIP).

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