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The Resource for your Nonhuman Primate Research

We support innovation, reproducibility, and translation of preclinical research with high-quality biological development. We offer primate antibodies and recombinant proteins for pre-clinical NHP studies, NHP-specific reagents for in vitro assays, and have an industry wide antibody reactivity database for NHP species.

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Therapeutics (in Vivo)

Antibodies for Assays

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Proteins

Reactivity Database

Recent Publications Using Our Reagents...

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NHPRR Product Catalog

Assay Reagent Catalog

New World Monkey Reagents

New World Spp (in vitro and in vivo)

NHPRR Therapeutics Catalog

Anti-Complement Antibodies
Anti-Cytokine/Chemokine and Receptors
Blocking Antibodies (Receptor-Ligand Antagonists)
Cell-Depleting Antibodies
Controls and Anti-Infectives
Fc-Fusion Proteins
Proteins & Enzymes
Serial Intravascular Staining (SIVS)
Stimulating Antibodies (Receptor-Ligand Agonists)

NHPRR News and Announcements

Follow the latest news on NHPRR's LinkedIn account and News Archives

NHP Reactivity

💬 Share your thoughts on a new chat-based tool for querying reagents 🚀

What questions would you want answered?

2025 May 20

B cell lines fail to support efficient rhesus enteric calicivirus and human norovirus replication.

Farkas, Tibor

J Virol

Reactivity Database or Legacy Product

2025 May 15

Convergence and divergence of B cell responses in two HIV-1 Env immunizations in Rhesus macaques.

DeLuca, Jenna M Blasi, Maria McGee, Taylor J Jha, Shalini Shen, Xiaoying Gu, Shuqin Pollara, Justin Kerkau, Melissa Purwar, Mansi Carnathan, Diane G Negri, Donatella Cara, Andrea Wollenberg, Kurt Wiehe, Kevin Saunders, Kevin O Lu, Shan Silvestri, Guido Weiner, David B Klotman, Mary E Ferrari, Guido Anthony Moody, M Bonsignori, Mattia

Commun Med (Lond)

Cell line secreting Herpesvirus Papio [S594]

2025 April 15

The saponin monophosphoryl lipid A nanoparticle adjuvant induces dose-dependent HIV vaccine responses in nonhuman primates.

Ramezani-Rad, Parham Marina-Zárate, Ester Maiorino, Laura Myers, Amber Kaczmarek Michaels, Katarzyna Pires, Ivan S Bloom, Nathaniel I Melo, Mariane B Lemnios, Ashley A Lopez, Paul G Cottrell, Christopher A Burton, Iszac Groschel, Bettina Pradhan, Arpan Stiegler, Gabriela Budai, Magdolna Kumar, Daniel Pallerla, Sam Sayeed, Eddy Sagar, Sangeetha L Kasturi, Sudhir Pai Van Rompay, Koen Ka Hangartner, Lars Wagner, Andreas Burton, Dennis R Schief, William R Crotty, Shane Irvine, Darrell J

J Clin Invest

Anti-CD38 [OKT10]

2025 April 07

Intravenous BCG-mediated protection against tuberculosis requires CD4+ T cells and CD8a+ lymphocytes.

Simonson, Andrew W Zeppa, Joseph J Bucsan, Allison N Chao, Michael C Pokkali, Supriya Hopkins, Forrest Chase, Michael R Vickers, Andrew J Sutton, Matthew S Winchell, Caylin G Myers, Amy J Ameel, Cassaundra L Kelly, Ryan J Krouse, Ben Hood, Luke E Li, Jiaxiang Lehman, Chelsea C Kamath, Megha Tomko, Jaime Rodgers, Mark A Donlan, Rachel Chishti, Harris Borish, H Jacob Klein, Edwin Scanga, Charles A Fortune, Sarah M Lin, Philana Ling Maiello, Pauline Roederer, Mario Darrah, Patricia A Seder, Robert A Flynn, JoAnne L

J Exp Med

Anti-CD8 beta [CD8b255R1] Anti-CD4 [CD4R1] Anti-CD8 alpha [MT807R1]

News & Updates:

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2024 Aug 23

mAbsolve Parnership for Fc-silenced STR Antibodies

Today, we celebrate a milestone—partnering with mAbsolve to incorporate ‘STR’ mutations into our antibodies. This ensures targeted action without unintended immune responses, boosting rigor, effectiveness, and safety. By decreasing Fc-mediated interference (hello Fc-block!) and enhancing the signal-to-noise ratio, STR-enhanced antibodies will produce more robust and reproducible scientific findings. Expect many STR-enhanced antibodies soon!

For your Acknowledgements section

Reagents used in these studies were provided by the NIH Nonhuman Primate Reagent Resource (P40 OD028116, U24 AI126683).

2024 Apr 11

NHPRR Linkedin

Follow our newest publications, products, and messages on LinkedIn!

RRID Citation on Materials and Methods

For your Materials & Methods section: The rhesus recombinant Anti-CD8 beta [CD8b255R1] monoclonal antibody was engineered and produced by the Nonhuman Primate Reagent Resource (NIH Nonhuman Primate Reagent Resource Cat# PR-2557, RRID:AB_2716321)

Anti-CD8 beta [CD8b255R1]

Contribute to the Resource

Help Us By:

Sharing Your Data: Our community-based reactivity database is built by users like you. Share your results!

Requesting a Reagent: We develop NHP-specific antibodies based on investigator-initiated requests, including: recombinant proteins for cell depletion, receptor activation, cytokine neutralization, co-stimulatory blockade, immunosuppression.

Licensing Our Reagents: Interested in using our antibodies on your assays? Reach us!

Sharing Your Publication: If you’ve recently published a study using an NHPRR reagent, add it to the publication database.

Share Your Data:

Now you can directly contribute your experimental data to our reactivity datatase. Send us your beautiful graphs and figures!

SHARE YOUR DATA

Request a Reagent:

Would you like to see an NHP-specific antibody developed through the program? Suggest a new reagent that would benefit the NHP community.

REQUEST A REAGENT

License Our Reagents:

We have species-specific reagents for preclinical studies in monkeys. Reach us if you are interested in learning about reagent partnerships.

LICENSE OUR REAGENTS

Share Your Publication:

We continue to grow the publication database so that peer-reviewed results can inform future research decisions.

SHARE YOUR PUBLICATION

The Nonhuman Primate Reagent Resource (NHPRR) is a nonprofit laboratory established in 1999, and supported by the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), and Office of Research Infrastructure Programs (ORIP).